αvβ1 integrin-IN-1


Catalog No. Size PriceQuantity
M27756-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects.

Product information

CAS Number: 1689540-62-2

Molecular Weight: 558.65

Formula: C26H34N6O6S

Chemical Name: (2S)-2-{[(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]formamido}-3-(4-{5-[(diaminomethylidene)amino]pentanamido}phenyl)propanoic acid

Smiles: NC(N)=NCCCCC(=O)NC1=CC=C(C[C@H](NC(=O)[C@@H]2CCCN2S(=O)(=O)C2=CC=CC=C2)C(O)=O)C=C1

InChiKey: BLLLAUHTNAVSQR-VXKWHMMOSA-N

InChi: InChI=1S/C26H34N6O6S/c27-26(28)29-15-5-4-10-23(33)30-19-13-11-18(12-14-19)17-21(25(35)36)31-24(34)22-9-6-16-32(22)39(37,38)20-7-2-1-3-8-20/h1-3,7-8,11-14,21-22H,4-6,9-10,15-17H2,(H,30,33)(H,31,34)(H,35,36)(H4,27,28,29)/t21-,22-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

αvβ1 integrin-IN-1 (Compound C8) significantly reduces the fibrotic markers in mouse model for liver and lung fibrosis.

Products are for research use only. Not for human use.

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