Description
αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects.
Product information
CAS Number: 1689540-62-2
Molecular Weight: 558.65
Formula: C26H34N6O6S
Chemical Name: (2S)-2-{[(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]formamido}-3-(4-{5-[(diaminomethylidene)amino]pentanamido}phenyl)propanoic acid
Smiles: NC(N)=NCCCCC(=O)NC1=CC=C(C[C@H](NC(=O)[C@@H]2CCCN2S(=O)(=O)C2=CC=CC=C2)C(O)=O)C=C1
InChiKey: BLLLAUHTNAVSQR-VXKWHMMOSA-N
InChi: InChI=1S/C26H34N6O6S/c27-26(28)29-15-5-4-10-23(33)30-19-13-11-18(12-14-19)17-21(25(35)36)31-24(34)22-9-6-16-32(22)39(37,38)20-7-2-1-3-8-20/h1-3,7-8,11-14,21-22H,4-6,9-10,15-17H2,(H,30,33)(H,31,34)(H,35,36)(H4,27,28,29)/t21-,22-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
αvβ1 integrin-IN-1 (Compound C8) significantly reduces the fibrotic markers in mouse model for liver and lung fibrosis.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.