Description
(2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 851961-99-4
Molecular Weight: 319.44
Formula: C13H21NO4S2
Chemical Name: 1-(pyridin-2-yl)-5,8,11-trioxa-1,2-dithiatridecan-13-ol
Smiles: OCCOCCOCCOCCSSC1=CC=CC=N1
InChiKey: NVGYTXVKRZYCDH-UHFFFAOYSA-N
InChi: InChI=1S/C13H21NO4S2/c15-5-6-16-7-8-17-9-10-18-11-12-19-20-13-3-1-2-4-14-13/h1-4,15H,5-12H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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