Zoxazolamine


Catalog No. Size PriceQuantity
M30164-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Zoxazolamine is widely used for a pharmacologic test that serves as a convenient indicator of changes in cytochrome P-450 activity in rodents.

Product information

CAS Number: 61-80-3

Molecular Weight: 168.58

Formula: C7H5ClN2O

Chemical Name: 5-chloro-1,3-benzoxazol-2-amine

Smiles: NC1=NC2=CC(Cl)=CC=C2O1

InChiKey: YGCODSQDUUUKIV-UHFFFAOYSA-N

InChi: InChI=1S/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (593.19 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Zoxazolamine is widely used for a pharmacologic test that serves as a convenient indicator of changes in cytochrome P-450 activity in rodents. The time-averaged serum clearance determined from tested concentrations data is 7.22±1.01 mL/min/kg for Zoxazolamine. Infusion of Zoxazolamine to righting reflex (LRR) at three different rates shows increasing Zoxazolamine concentration in serum and brain at the onset of the effect with increasing infusion rates. When the Zoxazolamine infusion is continued for 5 min beyond the onset of LRR, the concentrations of Zoxazolamine in the cerebrospinal fluid (CSF) at the offset of LRR are essentially identical to the onset concentrations.

Products are for research use only. Not for human use.

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