Description
X5050 is a REST inhibitor, with an EC50 of 2.1 μM.
Product information
CAS Number: 2404756-81-4
Molecular Weight: 309.32
Formula: C17H15N3O3
Chemical Name: 2-(2-hydroxyphenyl)-N-(prop-2-en-1-yloxy)-1H-1,3-benzodiazole-6-carboxamide
Smiles: C=CCONC(=O)C1=CC2NC(=NC=2C=C1)C1=CC=CC=C1O
InChiKey: RGROIKJLROTDCR-UHFFFAOYSA-N
InChi: InChI=1S/C17H15N3O3/c1-2-9-23-20-17(22)11-7-8-13-14(10-11)19-16(18-13)12-5-3-4-6-15(12)21/h2-8,10,21H,1,9H2,(H,18,19)(H,20,22)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (323.29 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
X5050 (100 µM, 1 day) induces a dosedependent decrease in the REST isoform in protein level.
In Vivo:
X5050 (2 x 2µl of 20 mM) is active in HD pathological context.
Products are for research use only. Not for human use.
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