X5050


Catalog No. Size PriceQuantity
M31881-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

X5050 is a REST inhibitor, with an EC50 of 2.1 μM.

Product information

CAS Number: 2404756-81-4

Molecular Weight: 309.32

Formula: C17H15N3O3

Chemical Name: 2-(2-hydroxyphenyl)-N-(prop-2-en-1-yloxy)-1H-1,3-benzodiazole-6-carboxamide

Smiles: C=CCONC(=O)C1=CC2NC(=NC=2C=C1)C1=CC=CC=C1O

InChiKey: RGROIKJLROTDCR-UHFFFAOYSA-N

InChi: InChI=1S/C17H15N3O3/c1-2-9-23-20-17(22)11-7-8-13-14(10-11)19-16(18-13)12-5-3-4-6-15(12)21/h2-8,10,21H,1,9H2,(H,18,19)(H,20,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (323.29 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

X5050 (100 µM, 1 day) induces a dosedependent decrease in the REST isoform in protein level.

In Vivo:

X5050 (2 x 2µl of 20 mM) is active in HD pathological context.

Products are for research use only. Not for human use.

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