Description
(E)-Ligustilide is isolated from Angelica sinensis and has nephroprotective effects.
Product information
CAS Number: 81944-08-3
Molecular Weight: 190.24
Formula: C12H14O2
Chemical Name: (3E)-3-butylidene-1,3,4,5-tetrahydro-2-benzofuran-1-one
Smiles: CCC/C=C1/OC(=O)C2C=CCCC=2/1
InChiKey: IQVQXVFMNOFTMU-DHZHZOJOSA-N
InChi: InChI=1S/C12H14O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7-8H,2-4,6H2,1H3/b11-8+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
(E)-Ligustilide (50 μM; 24-72 hours) decreases HK-2 cell survival to 86%, to 67% and to 49% for 24, 48 or 72 hours incubation, respectively. (E)-Ligustilide (50 μM; 48-72 hours) alone decreases the metabolic activity to 87±6% and 71±8% after 48 and 72 h incubation, respectively, as compared to the control condition in HK-2 cells.
Products are for research use only. Not for human use.
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