Vitamin B15

Vitamin B15 (Pangamic Acid) is a natural, ubiquitously in plant seeds substance and can used be as an agent stimulating cellular respiration. Vitamin B15 contains D-gluconodimethyl amino acetic acid. Vitamin B15 is also a immune-correcting agent. Vitamin B15 can be used for wide range of diseases.

Product information

CAS Number: 20858-86-0

Molecular Weight: 281.26

Formula: C10H19NO8

Chemical Name: (2R,3S,4R,5R)-6-{[2-(dimethylamino)acetyl]oxy}-2,3,4,5-tetrahydroxyhexanoic acid

Smiles: CN(C)CC(=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O

InChiKey: ZQTHOIGMSJMBLM-BUJSFMDZSA-N

InChi: InChI=1S/C10H19NO8/c1-11(2)3-6(13)19-4-5(12)7(14)8(15)9(16)10(17)18/h5,7-9,12,14-16H,3-4H2,1-2H3,(H,17,18)/t5-,7-,8+,9-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 250 mg/mL (888.86 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Unequivocal reports on identity and functions of Vitamin B15 (Pangamic Acid) in the literature make it impossible, however, to accurately assess either its chemical identity or its biological or medical functions. Indeed, the chemical identity of genuine Vitamin B15 (Pangamic Acid) has apparently never been ascertained or verifiably chemically identified as being the molecular weight 281-ester of DMG and gluconic acid claimed by Krebs and some Russian authors, and there is considerable doubt that such a stable substance exists with the straight chain sugar gluconic acid. Vitamin B15 (Pangamic Acid) is identified as a substance most likely containing both a sugar and a dimethylamine group.

In Vivo:

Addition of Vitamin B15 (Pangamic Acid) to the diet (Wistar rats; 2.5 mg/100 g of diet) increases the degree of fatty infiltration of the liver which is maintained at a stable level throughout the whole experiment, i.e. 12-18 months. Vitamin B15 (Pangamic Acid) enriches in the rat diet reduced glutathione peroxidase (after one year) and also glutathione transferase (after 18 months) in the brains of the animals, thus impairing their antioxidative capacities. Vitamin B15 (Pangamic Acid) treatment increase the cytochrome oxidase- and also succinate dehydrogenase-activity in certain rat tissues.

Products are for research use only. Not for human use.