Description
(S)-ZINC-3573 is an inactive enantiomer of ZINC-3573. (R)-ZINC-3573 is a selective MRGPRX2 agonist. (S)-ZINC-3573 and (R)-ZINC3573 are effective and internally controlled probe-pairs for investigating the biology of primate-exclusive receptor.
Product information
CAS Number: 2095596-11-3
Molecular Weight: 307.39
Formula: C18H21N5
Chemical Name: (3S)-N,N-dimethyl-1-{5-phenylpyrazolo[1,5-a]pyrimidin-7-yl}pyrrolidin-3-amine
Smiles: CN(C)[C@@H]1CN(CC1)C1=CC(=NC2=CC=NN21)C1C=CC=CC=1
InChiKey: XKBSPAZCFAIBJL-HNNXBMFYSA-N
InChi: InChI=1S/C18H21N5/c1-21(2)15-9-11-22(13-15)18-12-16(14-6-4-3-5-7-14)20-17-8-10-19-23(17)18/h3-8,10,12,15H,9,11,13H2,1-2H3/t15-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
(S)-ZINC-3573 displays no activity on MRGPRX2 at concentrations below 100 μM.
In Vivo:
(R)-ZINC-3573阴性对照
Products are for research use only. Not for human use.
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