Description
Xanthine oxidase-IN-16 is potent and orally active xanthine oxidase (XO) inhibitor with an IC50 of 102 nM. Xanthine oxidase-IN-16 shows significant efficacy in hyperuricemia rats.
Product information
Molecular Weight: 297.31
Formula: C17H15NO4
Smiles: CNC1C=CC(=CC=1)C(=O)/C=C/C1=CC(=CC=C1O)C(O)=O
InChiKey: ASANMKNBNVEBPD-XBXARRHUSA-N
InChi: InChI=1S/C17H15NO4/c1-18-14-6-2-11(3-7-14)15(19)8-4-12-10-13(17(21)22)5-9-16(12)20/h2-10,18,20H,1H3,(H,21,22)/b8-4+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Xanthine oxidase-IN-16 (compound 12h; 10-40 mg/kg; po; once) exhibits a significant hypouricemic effect on Potassium oxonate (HY-17511)-induced hyperuricemia rats.
Products are for research use only. Not for human use.
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