Description
Vatalanib, also known as PTK787, is an orally bioavailable anilinophthalazine with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.
Product information
CAS Number: 212141-51-0
Molecular Weight: 419.73
Formula: C20H17Cl3N4
Synonym:
PTK/ZK
CGP-79787D
CGP-79787
Chemical Name: N-(4-chlorophenyl)-4-[(pyridin-4-yl)methyl]phthalazin-1-amine dihydrochloride
Smiles: Cl.Cl.ClC1C=CC(=CC=1)NC1=NN=C(CC2C=CN=CC=2)C2=CC=CC=C21
InChiKey: AZUQEHCMDUSRLH-UHFFFAOYSA-N
InChi: InChI=1S/C20H15ClN4.2ClH/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;;/h1-12H,13H2,(H,23,25);2*1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.