Enniatin A1


Catalog No. Size PriceQuantity
M11801-2 2mg solid $1,360
M11801-10 10mg solid $5,440

Description

Enniatin A1 isolated from Fusarium mycotoxins is a cyclic hexadepsipeptide consisting of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids. Enniatin A1 possesses anticarcinogenic properties by induction of apoptosis and disruption of ERK signalling pathway. Enniatin A1 inhibits ACAT with an IC50 of 49 μM in rat liver microsomes.

Product information

CAS Number: 4530-21-6

Molecular Weight: 667.87

Formula: C35H61N3O9

Chemical Name: (3S, 6R, 12R, 15S, 18R)-3, 9-bis[(2S)-butan-2-yl]-4, 10, 16-trimethyl-6, 12, 15, 18-tetrakis(propan-2-yl)-1, 7, 13-trioxa-4, 10, 16-triazacyclooctadecane-2, 5, 8, 11, 14, 17-hexone

Smiles: CC(C)[C@H]1C(=O)O[C@H](C(C)C)C(=O)N(C)C([C@@H](C)CC)C(=O)O[C@H](C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)C(=O)O[C@H](C(C)C)C(=O)N1C

InChiKey: OWUREPXBPJFMOK-YXRMYXQLSA-N

InChi: InChI=1S/C35H61N3O9/c1-16-22(11)25-34(43)46-27(19(5)6)30(39)36(13)24(18(3)4)33(42)45-28(20(7)8)31(40)37(14)26(23(12)17-2)35(44)47-29(21(9)10)32(41)38(25)15/h18-29H,16-17H2,1-15H3/t22-,23-,24-,25-,26?,27+,28+,29+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Wätjen W, et al. Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Mol Nutr Food Res. 2009 Apr;53(4):431-40.

Products are for research use only. Not for human use.

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