Description
Myricetin is a COMT inhibitor found in fruits and vegetables. It exhibits a wide variety of biological activities, including decreasing cholesterol, triglyceride, and lipid levels, inhibiting amyloid-B-induced neurodegeneration, activating Wnt/B-catenin signaling to increase osteoclast differentiation, and inducing cell cycle arrest in oral squamous cell carcinoma cells.
Product information
CAS Number: 529-44-2
Molecular Weight: 318.24
Formula: C15H10O8
Synonym:
Cannabiscetin
HSDB 7682
HSDB7682
HSDB-7682
Chemical Name: 3, 5, 7-trihydroxy-2-(3, 4, 5-trihydroxyphenyl)-4H-chromen-4-one
Smiles: OC1C=C(C=C(O)C=1O)C1OC2C=C(O)C=C(O)C=2C(=O)C=1O
InChiKey: IKMDFBPHZNJCSN-UHFFFAOYSA-N
InChi: InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 63 mg/mL(197.96 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Myricetin(Cannabiscetin) is a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which has antioxidant and anti tumor properties. Myricetin has antioxidant properties. In vitro research suggests that myricetin in high concentrations can modify LDL cholesterol such that uptake by white blood cells is increased. Studies shows that high myricetin consumption reduces the risk of prostate cancer and pancreatic cancer.
References:
- Phillips PA, et al. Cancer Lett, 2011, 308(2), 181-188.
- Nothlings U, et al. Am J Epidemiol, 2007, 166(8), 924-931.
- Knekt P, et al. Am J Clin Nutr, 2002, 76(3), 560-568.
Products are for research use only. Not for human use.
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