Description
Rhosin is an inhibitor of RhoA and RhoC interaction with GEFs. It acts by preventing RhoA activation and downstream MLC phosphorylation, filamentous actin formation and focal adhesion assembly without perturbing endogenous Cdc42 or Rac signalling.
Product information
CAS Number: 1173671-63-0
Molecular Weight: 358.40
Formula: C20H18N6O
Chemical Name: (2R)-2-amino-3-(1H-indol-3-yl)-N'-[(1E)-(quinoxalin-6-yl)methylidene]propanehydrazide
Smiles: N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N/N=C/C1=CC2=NC=CN=C2C=C1
InChiKey: FGYHLIHEFHCMPP-FVWOBLMASA-N
InChi: InChI=1S/C20H18N6O/c21-16(10-14-12-24-17-4-2-1-3-15(14)17)20(27)26-25-11-13-5-6-18-19(9-13)23-8-7-22-18/h1-9,11-12,16,24H,10,21H2,(H,26,27)/b25-11+/t16-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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