Description
FTI-277 is a ras CAAX (C - Cys; A - aliphatic amino acid; X - Ser or Met) peptidomimetic that inhibits farnesyltransferase and blocks Ras oncogenic signaling by accumulating Ras/Raf complexes in the cytoplasm.
Product information
CAS Number: 170006-73-2
Molecular Weight: 447.61
Formula: C22H29N3O3S2
Chemical Name: methyl (2S)-2-[(5-{[(2R)-2-amino-3-sulfanylpropyl]amino}-[1,1'-biphenyl]-2-yl)formamido]-4-(methylsulfanyl)butanoate
Smiles: COC(=O)[C@H](CCSC)NC(=O)C1=CC=C(C=C1C1C=CC=CC=1)NC[C@@H](N)CS
InChiKey: GKFPROVOIQKYTO-UZLBHIALSA-N
InChi: InChI=1S/C22H29N3O3S2/c1-28-22(27)20(10-11-30-2)25-21(26)18-9-8-17(24-13-16(23)14-29)12-19(18)15-6-4-3-5-7-15/h3-9,12,16,20,24,29H,10-11,13-14,23H2,1-2H3,(H,25,26)/t16-,20+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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