FTI-277


Catalog No. Size PriceQuantity
M8989-2 Solid 2 mg $150
M8989-10 Solid 10 mg $450

Description

FTI-277 is a ras CAAX (C - Cys; A - aliphatic amino acid; X - Ser or Met) peptidomimetic that inhibits farnesyltransferase and blocks Ras oncogenic signaling by accumulating Ras/Raf complexes in the cytoplasm.

Product information

CAS Number: 170006-73-2

Molecular Weight: 447.61

Formula: C22H29N3O3S2

Chemical Name: methyl (2S)-2-[(5-{[(2R)-2-amino-3-sulfanylpropyl]amino}-[1,1'-biphenyl]-2-yl)formamido]-4-(methylsulfanyl)butanoate

Smiles: COC(=O)[C@H](CCSC)NC(=O)C1=CC=C(C=C1C1C=CC=CC=1)NC[C@@H](N)CS

InChiKey: GKFPROVOIQKYTO-UZLBHIALSA-N

InChi: InChI=1S/C22H29N3O3S2/c1-28-22(27)20(10-11-30-2)25-21(26)18-9-8-17(24-13-16(23)14-29)12-19(18)15-6-4-3-5-7-15/h3-9,12,16,20,24,29H,10-11,13-14,23H2,1-2H3,(H,25,26)/t16-,20+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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