Carvedilol phosphate hemihydrate - CAS# 610309-89-2


Catalog No. Size PriceQuantity
M17220-C Contact sales@xcessbio.com for quotation $100

Description

Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is a non-selective β/α-1 blocker. Carvedilol phosphate hemihydrate inhibits lipid peroxidation with an IC50 of 5 μM. Carvedilol phosphate hemihydrate is a multiple action antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol phosphate hemihydrate is an autophagy inducer that inhibits the NLRP3 inflammasome.

Product information

CAS Number: 610309-89-2

Molecular Weight: 513.48

Formula: C48H60N4O17P2

Chemical Name: bis(1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol) bis(phosphoric acid) hydrate

Smiles: O.COC1=CC=CC=C1OCCNCC(O)COC1C=CC=C2NC3C=CC=CC=3C=12.COC1=CC=CC=C1OCCNCC(O)COC1C=CC=C2NC3C=CC=CC=3C=12.OP(O)(O)=O.OP(O)(O)=O

InChiKey: LHNYXTULDSJZRB-UHFFFAOYSA-N

InChi: InChI=1S/2C24H26N2O4.2H3O4P.H2O/c2*1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20;2*1-5(2,3)4;/h2*2-12,17,25-27H,13-16H2,1H3;2*(H3,1,2,3,4);1H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Superoxide generation by activated human neutrophils in vitro is inhibited by Carvedilol with an IC50 of 28 μM. Carvedilol is shown to scavenge oxygen free radicals in a cell-free system with an IC50 of 25 μM.

Products are for research use only. Not for human use.

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