4'-Hydroxy-2, 4-dimethoxychalcone. CAS# 151135-64-7


Catalog No. Size PriceQuantity
M25590-2 2 mg solid $150
M25590-10 10 mg solid $515
M25590-C Contact sales@xcessbio.com for quotation $100

Description

4'-Hydroxy-2, 4-dimethoxychalcone, CAS No. 151135-64-7, is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2, 4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity.

Product information

CAS Number: 151135-64-7

Molecular Weight: 284.31

Formula: C17H16O4

Chemical Name: (2E)-3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one

Smiles: COC1=CC(OC)=C(C=C1)/C=C/C(=O)C1C=CC(O)=CC=1

InChiKey: LNEYYODFMSUKGY-UXBLZVDNSA-N

InChi: InChI=1S/C17H16O4/c1-20-15-9-5-13(17(11-15)21-2)6-10-16(19)12-3-7-14(18)8-4-12/h3-11,18H,1-2H3/b10-6+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC50=4.2 μM) and W2 (IC50=4.8 μM).

In Vivo:

4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T1/2 of 1.94 hours, a Cmax of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice.

Products are for research use only. Not for human use.

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