Description
Anti-MRSA agent 18 (E17) is an inhibitor of MRSA with MIC values of 2 μg/mL for S. aureus and 4 μg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death.
Product information
Molecular Weight: 715.55
Formula: C36H42BrCl2N3O3
Smiles: [Br-].CCCCNC(=O)C[N+](C)(C)CCCOC1=CC=C(C=C1CC=C)C1=CC(CC=C)=CC2N=C(OC=21)C1C(Cl)=CC=CC=1Cl
InChiKey: ITGSARGDSRKJQW-UHFFFAOYSA-N
InChi: InChI=1S/C36H41Cl2N3O3.BrH/c1-6-9-18-39-33(42)24-41(4,5)19-11-20-43-32-17-16-26(23-27(32)13-8-3)28-21-25(12-7-2)22-31-35(28)44-36(40-31)34-29(37)14-10-15-30(34)38;/h7-8,10,14-17,21-23H,2-3,6,9,11-13,18-20,24H2,1,4-5H3;1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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