Description
MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein that selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains. MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.
Product information
CAS Number: 509102-00-5
Molecular Weight: 347.43
Formula: C17H21N3O3S
Synonym:
MIM 1
MIM-1
Inhibitor of Mcl-1
Chemical Name: 4-[(1E)-{[2-(cyclohexylimino)-4-methyl-2,3-dihydro-1,3-thiazol-3-yl]imino}methyl]benzene-1,2,3-triol
Smiles: CC1=CSC(=NC2CCCCC2)N1/N=C/C1=CC=C(O)C(O)=C1O
InChiKey: RGGFUBMUOVFZEF-LDRVEFRDSA-N
InChi: InChI=1S/C17H21N3O3S/c1-11-10-24-17(19-13-5-3-2-4-6-13)20(11)18-9-12-7-8-14(21)16(23)15(12)22/h7-10,13,21-23H,2-6H2,1H3/b18-9+,19-17-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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