Description
RU 58642 is an orally active non-steroidal antiandrogen, which displays a strong and selective affinity for androgen receptor.
Product information
CAS Number: 143782-63-2
Molecular Weight: 336.27
Formula: C15H11F3N4O2
Smiles: CC1(C)C(=O)N(C2=CC=C(C#N)C(=C2)C(F)(F)F)C(=O)N1CC#N
InChiKey: ZVWXHSNUBLIKJH-UHFFFAOYSA-N
InChi: InChI=1S/C15H11F3N4O2/c1-14(2)12(23)22(13(24)21(14)6-5-19)10-4-3-9(8-20)11(7-10)15(16,17)18/h3-4,7H,6H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
In vivo, the antiandrogenic activity of RU-58642 is evaluated in castrated rat supplemented with testosterone propionate and in intact animals on prostate, seminal vesicles weight and serum levels of testosterone by oral and subcutaneous route. In rats, RU 58642 induces a significant decrease in prostate weight at a dose as low as 0.3 mg/kg whatever the route of administration.
Products are for research use only. Not for human use.
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