RU 58642


Catalog No. Size PriceQuantity
M34257-C Contact sales@xcessbio.com for quotation $100

Description

RU 58642 is an orally active non-steroidal antiandrogen, which displays a strong and selective affinity for androgen receptor.

Product information

CAS Number: 143782-63-2

Molecular Weight: 336.27

Formula: C15H11F3N4O2

Smiles: CC1(C)C(=O)N(C2=CC=C(C#N)C(=C2)C(F)(F)F)C(=O)N1CC#N

InChiKey: ZVWXHSNUBLIKJH-UHFFFAOYSA-N

InChi: InChI=1S/C15H11F3N4O2/c1-14(2)12(23)22(13(24)21(14)6-5-19)10-4-3-9(8-20)11(7-10)15(16,17)18/h3-4,7H,6H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

In vivo, the antiandrogenic activity of RU-58642 is evaluated in castrated rat supplemented with testosterone propionate and in intact animals on prostate, seminal vesicles weight and serum levels of testosterone by oral and subcutaneous route. In rats, RU 58642 induces a significant decrease in prostate weight at a dose as low as 0.3 mg/kg whatever the route of administration.

Products are for research use only. Not for human use.

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