SDZ 224-015 - CAS# 161511-45-1


Catalog No. Size PriceQuantity
M17815-C Contact sales@xcessbio.com for quotation $100

Description

SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1.

Product information

CAS Number: 161511-45-1

Molecular Weight: 652.52

Formula: C30H35Cl2N3O9

Chemical Name: ethyl (3S)-3-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]propanamido]-5-(2, 6-dichlorobenzoyloxy)-4-oxopentanoate

Smiles: CC(C)[C@H](NC(=O)OCC1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)OCC)C(=O)COC(=O)C1C(Cl)=CC=CC=1Cl

InChiKey: VMKPCENEHPIWJT-DOPYIHRPSA-N

InChi: InChI=1S/C30H35Cl2N3O9/c1-5-42-24(37)14-22(23(36)16-43-29(40)25-20(31)12-9-13-21(25)32)34-27(38)18(4)33-28(39)26(17(2)3)35-30(41)44-15-19-10-7-6-8-11-19/h6-13,17-18,22,26H,5,14-16H2,1-4H3,(H,33,39)(H,34,38)(H,35,41)/t18-,22-,26-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

SDZ 224-015 (0.3-300 μg/kg) potently reduces carrageenin-induced paw oedema. SDZ 224-015 (0.2-5 mg/kg, p.o.) displays analgesic activity in the Randall-Selitto yeast-inflamed paw pressure test, significant at a dose of 1 mg/kg.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed