Description
Cathepsin L-IN-5 (D6-3) is a potent Cathepsin L (CatL) inhibitor with an IC50 of 0.27 nM. Cathepsin L-IN-5 effectively blocks the CatL function and substantially hinders the entry of the SARS-CoV-2 pseudovirus to cells by inhibiting the cleavage of the spike protein. Cathepsin L-IN-5 can be utilized in infection research.
Product information
Molecular Weight: 516.99
Formula: C30H26ClFN2O3
Chemical Name: N-((S)-1-(((S)-4-chloro-3-oxo-1-phenylbutan-2-yl)amino)-3-(4-fluorophenyl)-1-oxopropan-2-yl)-1-naphthamide
Smiles: O=C(N[C@@H](CC1C=CC=CC=1)C(=O)CCl)[C@H](CC1C=CC(F)=CC=1)NC(=O)C1=CC=CC2=CC=CC=C21
InChiKey: FUEYCNUHTBZPRF-SVBPBHIXSA-N
InChi: InChI=1S/C30H26ClFN2O3/c31-19-28(35)26(17-20-7-2-1-3-8-20)33-30(37)27(18-21-13-15-23(32)16-14-21)34-29(36)25-12-6-10-22-9-4-5-11-24(22)25/h1-16,26-27H,17-19H2,(H,33,37)(H,34,36)/t26-,27-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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