Description
MK-3207 is a potent and orally active calcitonin gene-related peptide receptor antagonist. Calcitonin gene related peptide (CGRP) receptor antagonists are effective acute migraine treatments. (Ki = 0.024 nM).
Product information
CAS Number: 957118-49-9
Molecular Weight: 557.59
Formula: C31H29F2N5O3
Chemical Name: 2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-6-yl]acetamide
Smiles: O=C(CN1[C@@H](CNC2(CCCC2)C1=O)C1C=C(F)C=C(F)C=1)NC1=CC2C[C@]3(CC=2C=C1)C1=CC=CN=C1NC3=O
InChiKey: AZAANWYREOQRFB-SETSBSEESA-N
InChi: InChI=1S/C31H29F2N5O3/c32-21-10-19(11-22(33)13-21)25-16-35-31(7-1-2-8-31)29(41)38(25)17-26(39)36-23-6-5-18-14-30(15-20(18)12-23)24-4-3-9-34-27(24)37-28(30)40/h3-6,9-13,25,35H,1-2,7-8,14-17H2,(H,36,39)(H,34,37,40)/t25-,30+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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