Vazegepant hydrochloride - CAS# 1414976-20-7


Catalog No. Size PriceQuantity
M17030-C Contact sales@xcessbio.com for quotation $100

Description

Vazegepant (BHV-3500) hydrochloride is a highly affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant hydrochloride is the first intranasal gepant for migraine.

Product information

CAS Number: 1414976-20-7

Molecular Weight: 675.26

Formula: C36H47ClN8O3

Chemical Name: N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide hydrochloride

Smiles: Cl.CN1CCC(CC1)N1CCN(CC1)C(=O)[C@@H](CC1C=C2C=NNC2=C(C)C=1)NC(=O)N1CCC(CC1)C1=CC2=CC=CC=C2NC1=O

InChiKey: VQDUWCSSPSOSNA-RYWNGCACSA-N

InChi: InChI=1S/C36H46N8O3.ClH/c1-24-19-25(20-28-23-37-40-33(24)28)21-32(35(46)43-17-15-42(16-18-43)29-9-11-41(2)12-10-29)39-36(47)44-13-7-26(8-14-44)30-22-27-5-3-4-6-31(27)38-34(30)45;/h3-6,19-20,22-23,26,29,32H,7-18,21H2,1-2H3,(H,37,40)(H,38,45)(H,39,47);1H/t32-;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (74.05 mM; Need ultrasonic). H2O : 50 mg/mL (74.05 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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