Description
Letermovir, also known as MK-8828 and AIC-246, is an antiviral drug that is being developed for the treatment of cytomegalovirus (CVM) infections. Letermovir has been tested in CMV infected patients with allogeneic stem cell transplants and may also be useful for other patients with a compromised immune system such as those with organ transplants or HIV infections.
Product information
CAS Number: 917389-32-3
Molecular Weight: 572.55
Formula: C29H28F4N4O4
Synonym:
AIC246
AIC 246
AIC-246
Chemical Name: 2-[(4S)-8-fluoro-3-[2-methoxy-5-(trifluoromethyl)phenyl]-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3,4-dihydroquinazolin-4-yl]acetic acid
Smiles: COC1C=C(C=CC=1)N1CCN(CC1)C1=NC2C(=CC=CC=2F)[C@H](CC(O)=O)N1C1=CC(=CC=C1OC)C(F)(F)F
InChiKey: FWYSMLBETOMXAG-QHCPKHFHSA-N
InChi: InChI=1S/C29H28F4N4O4/c1-40-20-6-3-5-19(16-20)35-11-13-36(14-12-35)28-34-27-21(7-4-8-22(27)30)23(17-26(38)39)37(28)24-15-18(29(31,32)33)9-10-25(24)41-2/h3-10,15-16,23H,11-14,17H2,1-2H3,(H,38,39)/t23-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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