Description
SCH 563705 is a CXCR2/CXCR1 antagonist. SCH563705 selectively reduced the peripheral blood neutrophil frequency, and caused an elevation in the CXCR2 ligand CXCL1. SCH-563705 may have therapeutic potential for targeting CXCR2/CXCR1 in human arthritides.
Product information
CAS Number: 473728-58-4
Molecular Weight: 425.48
Formula: C23H27N3O5
Chemical Name: 3-[(3,4-dioxo-2-{[(1R)-1-[4-(propan-2-yl)furan-2-yl]propyl]amino}cyclobut-1-en-1-yl)amino]-2-hydroxy-N,N-dimethylbenzamide
Smiles: CC(C)C1C=C(OC=1)[C@@H](CC)NC1=C(NC2=CC=CC(C(=O)N(C)C)=C2O)C(=O)C1=O
InChiKey: DGKQQEVYYPCMNE-OAHLLOKOSA-N
InChi: InChI=1S/C23H27N3O5/c1-6-15(17-10-13(11-31-17)12(2)3)24-18-19(22(29)21(18)28)25-16-9-7-8-14(20(16)27)23(30)26(4)5/h7-12,15,24-25,27H,6H2,1-5H3/t15-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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