Description
TAK-700, is an orally bioavailable non-steroidal androgen synthesis inhibitor of steroid 17alpha-monooxygenase (17, 20 lyase) with potential antiandrogen activity. TAK-700 binds to and inhibits the steroid 17alpha-monooxygenase in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen-dependent growth signaling and may inhibit cell proliferation of androgen-dependent tumor cells.
Product information
CAS Number: 566939-85-3
Molecular Weight: 307.35
Formula: C18H17N3O2
Synonym:
Orteronel
Related CAS Number:
426219-18-3 (Orteronel (racemic))
Chemical Name: (S)-6-(7-hydroxy-6, 7-dihydro-5H-pyrrolo[1, 2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Smiles: CNC(=O)C1=CC2=CC=C(C=C2C=C1)[C@@]1(O)CCN2C=NC=C12
InChiKey: OZPFIJIOIVJZMN-SFHVURJKSA-N
InChi: InChI=1S/C18H17N3O2/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21/h2-5,8-11,23H,6-7H2,1H3,(H,19,22)/t18-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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