AZ PFKFB3 26


Catalog No. Size PriceQuantity
M28114-C Contact sales@xcessbio.com for quotation $100
M28114-10S 10 mg solid $208

Description

AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively.

Product information

CAS Number: 1704740-52-2

Molecular Weight: 402.49

Formula: C24H26N4O2

Chemical Name: (2S)-N-(4-{[3-cyano-1-(2-methylpropyl)-1H-indol-5-yl]oxy}phenyl)pyrrolidine-2-carboxamide

Smiles: CC(C)CN1C=C(C#N)C2=CC(=CC=C12)OC1=CC=C(C=C1)NC(=O)[C@@H]1CCCN1

InChiKey: OOGHGWKBJXQNEJ-QFIPXVFZSA-N

InChi: InChI=1S/C24H26N4O2/c1-16(2)14-28-15-17(13-25)21-12-20(9-10-23(21)28)30-19-7-5-18(6-8-19)27-24(29)22-4-3-11-26-22/h5-10,12,15-16,22,26H,3-4,11,14H2,1-2H3,(H,27,29)/t22-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5 mg/mL (12.42 mM; ultrasonic and adjust pH to 3 with HCl).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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