TRPM4-IN-2


Catalog No. Size PriceQuantity
M34678-C Contact sales@xcessbio.com for quotation $100

Description

TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibitor with an IC50 value of 0.16 μM.

Product information

CAS Number: 667411-04-3

Molecular Weight: 355.77

Formula: C19H14ClNO4

Synonym:

TRPM4-IN-2

TRPM4 IN-2

Chemical Name: 4-chloro-2-(2-(naphthalen-1-yloxy)acetamido)benzoic acid

Smiles: OC(=O)C1=CC=C(Cl)C=C1NC(=O)COC1=CC=CC2=CC=CC=C21

InChiKey: OKFVCWAYHJMQFA-UHFFFAOYSA-N

InChi: InChI=1S/C19H14ClNO4/c20-13-8-9-15(19(23)24)16(10-13)21-18(22)11-25-17-7-3-5-12-4-1-2-6-14(12)17/h1-10H,11H2,(H,21,22)(H,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Borgström A, Hauert B, Kappel S, Zoni E, Kiener M, Stokłosa P, Baur R, Spahn M, Kruithof-de Julio M, Peinelt C. Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. J Mol Biol. 2021 Aug 20;433(17):166665. doi: 10.1016/j.jmb.2020.09.024. Epub 2020 Oct 12. PMID: 33058873.
  2. Stokłosa P, Borgström A, Hauert B, Baur R, Peinelt C. Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells. Cancers (Basel). 2021 Oct 28;13(21):5400. doi: 10.3390/cancers13215400. PMID: 34771564; PMCID: PMC8582472.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed