Description
TC-O9311 is a potent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells expressing human GPR139).
Product information
CAS Number: 444932-31-4
Molecular Weight: 365.38
Formula: C20H19N3O4
Synonym:
TC-O-9311
TCO-9311
TC-O 9311
TC-O9311
TCO 9311
TCO9311
Chemical Name: 3,5-dimethoxy-benzoic acid, 2-[(1-naphthalenylamino)carbonyl]hydrazide
Smiles: COC1C=C(C=C(C=1)OC)C(=O)NNC(=O)NC1=CC=CC2=CC=CC=C21
InChiKey: KPTMSQHTGZMEFU-UHFFFAOYSA-N
InChi: InChI=1S/C20H19N3O4/c1-26-15-10-14(11-16(12-15)27-2)19(24)22-23-20(25)21-18-9-5-7-13-6-3-4-8-17(13)18/h3-12H,1-2H3,(H,22,24)(H2,21,23,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
References:
- Shi F, Shen JK, Chen D, Fog K, Thirstrup K, Hentzer M, Karlsson JJ, Menon V, Jones KA, Smith KE, Smith G. Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139. ACS Med Chem Lett. 2011 Feb 28;2(4):303-6. doi: 10.1021/ml100293q. eCollection 2011 Apr 14. PubMed PMID: 24900311; PubMed Central PMCID: PMC4028000.
Products are for research use only. Not for human use.
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