RA-9


Catalog No. Size PriceQuantity
M7535-2 2mg solid $90
M7535-10 10mg solid $270

Description

RA-9 is a cell-permeable, potent and selective inhibitor of proteasome-associated deubiquitinating enzymes (DUBs) with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.

Product information

CAS Number: 919091-63-7

Molecular Weight: 365.34

Formula: C19H15N3O5

Chemical Name: (3E,5E)-3,5-Bis[(4-nitrophenyl)methylene]-4-piperidinone

Smiles: [O-][N+](=O)C1C=CC(/C=C2\CNC/C(=C\C3C=CC(=CC=3)[N+]([O-])=O)/C\2=O)=CC=1

InChiKey: YUYPWAMLWZVHAE-KAVGSWPWSA-N

InChi: InChI=1S/C19H15N3O5/c23-19-15(9-13-1-5-17(6-2-13)21(24)25)11-20-12-16(19)10-14-3-7-18(8-4-14)22(26)27/h1-10,20H,11-12H2/b15-9+,16-10+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 8 mg/mL (21.90 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Kathleen Coughlin, et al. Clin Cancer Res. 2014 Jun 15;20(12):

Products are for research use only. Not for human use.

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