BVDV-IN-1 - CAS# 345651-04-9


Catalog No. Size PriceQuantity
M17110-C Contact sales@xcessbio.com for quotation $100

Description

BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC).

Product information

CAS Number: 345651-04-9

Molecular Weight: 334.41

Formula: C20H22N4O

Chemical Name: 2-[4-(2-phenylquinazolin-4-yl)piperazin-1-yl]ethan-1-ol

Smiles: OCCN1CCN(CC1)C1=NC(=NC2=CC=CC=C21)C1C=CC=CC=1

InChiKey: DPFKMYSBAMEGQK-UHFFFAOYSA-N

InChi: InChI=1S/C20H22N4O/c25-15-14-23-10-12-24(13-11-23)20-17-8-4-5-9-18(17)21-19(22-20)16-6-2-1-3-7-16/h1-9,25H,10-15H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (747.59 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

BVDV-IN-1 (compound 1.9) binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp). BVDV-IN-1 inhibits the replication of TSC-resistant BVDV variants in vitro.

Products are for research use only. Not for human use.

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