Description
A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor.
Product information
CAS Number: 145307-34-2
Molecular Weight: 365.89
Formula: C20H28ClNO3
Chemical Name: (1R, 3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3, 4-dihydro-1H-2-benzopyran-5, 6-diol hydrochloride
Smiles: Cl.NC[C@@H]1O[C@@H](CC2=C1C=CC(O)=C2O)C12CC3CC(C1)CC(C2)C3
InChiKey: BWHPNJVKFAPVOG-QYFJGNGUSA-N
InChi: InChI=1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18-,20?;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake, due principally to a reduction in meal size and duration.
Products are for research use only. Not for human use.
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