A-77636 hydrochloride - CAS# 145307-34-2


Catalog No. Size PriceQuantity
M17848-C Contact sales@xcessbio.com for quotation $100

Description

A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor.

Product information

CAS Number: 145307-34-2

Molecular Weight: 365.89

Formula: C20H28ClNO3

Chemical Name: (1R, 3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3, 4-dihydro-1H-2-benzopyran-5, 6-diol hydrochloride

Smiles: Cl.NC[C@@H]1O[C@@H](CC2=C1C=CC(O)=C2O)C12CC3CC(C1)CC(C2)C3

InChiKey: BWHPNJVKFAPVOG-QYFJGNGUSA-N

InChi: InChI=1S/C20H27NO3.ClH/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20;/h1-2,11-13,17-18,22-23H,3-10,21H2;1H/t11?,12?,13?,17-,18-,20?;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake, due principally to a reduction in meal size and duration.

Products are for research use only. Not for human use.

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