Description
3-Methylglutaric acid, a leucine metabolite, is a conspicuous C6 dicarboxylic organic acid classically associated with two distinct leucine pathway enzyme deficiencies, 3-hydroxy-3-methylglutaryl CoA lyase (HMGCL) and 3-methylglutaconyl CoA hydratase (AUH).
Product information
CAS Number: 626-51-7
Molecular Weight: 146.14
Formula: C6H10O4
Chemical Name: 3-methylpentanedioic acid
Smiles: CC(CC(O)=O)CC(O)=O
InChiKey: XJMMNTGIMDZPMU-UHFFFAOYSA-N
InChi: InChI=1S/C6H10O4/c1-4(2-5(7)8)3-6(9)10/h4H,2-3H2,1H3,(H,7,8)(H,9,10)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Barich DH, et al. 3-Methylglutaric acid as a 13C solid-state NMR standard. Solid State Nucl Magn Reson. 2006 Oct;30(3-4):125-9.
- Dylan E Jones, et al. 3-Methylglutaric acid in energy metabolism. Clin Chim Acta. 2020 Mar;502:233-239.
Products are for research use only. Not for human use.
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