Description
FHT-1205 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 67).
Product information
CAS Number: 2368903-18-6
Molecular Weight: 555.69
Formula: C25H25N5O4S3
Smiles: CSCC[C@H](NC(=O)C1=CN(C=C1)S(C)(=O)=O)C(=O)NC1=NC(=CS1)C1=CC(=CC=C1)C1C=CN=CC=1
InChiKey: FAYSHZVDWADZMD-NRFANRHFSA-N
InChi: InChI=1S/C25H25N5O4S3/c1-35-13-9-21(27-23(31)20-8-12-30(15-20)37(2,33)34)24(32)29-25-28-22(16-36-25)19-5-3-4-18(14-19)17-6-10-26-11-7-17/h3-8,10-12,14-16,21H,9,13H2,1-2H3,(H,27,31)(H,28,29,32)/t21-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1.
Products are for research use only. Not for human use.
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