Description
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα. Urolithin B suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.
Product information
CAS Number: 1139-83-9
Molecular Weight: 212.20
Formula: C13H8O3
Chemical Name: 3-hydroxy-6H-benzo[c]chromen-6-one
Smiles: OC1=CC2OC(=O)C3=CC=CC=C3C=2C=C1
InChiKey: WXUQMTRHPNOXBV-UHFFFAOYSA-N
InChi: InChI=1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO 42 mg/mL (197.93 mM) Ethanol 12 mg/mL (56.55 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Gyeongjin Lee, et al. Phytomedicine. 2019 Mar 1;55:50-57.
- Julie Rodriguez, et al. J Cachexia Sarcopenia Muscle. 2017 Au
Products are for research use only. Not for human use.
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