TSU-68 - CAS# 252916-29-3


Catalog No. Size PriceQuantity
M10908-2 Solid 2 mg $90
M10908-10 Solid 10 mg $270

Description

Orantinib, also known as TSU-68;SU6668, is an orally bioavailable receptor tyrosine kinase inhibitor. Orantinib binds to and inhibits the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), thereby inhibiting angiogenesis and cell proliferation. Orantinib also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. Check for active clinical trials or closed clinical trials using this agent.

Product information

CAS Number: 252916-29-3

Molecular Weight: 310.35

Formula: C18H18N2O3

Synonym:

SU 6668

TSU68

TSU 68

SU6668

Chemical Name: 3-{2, 4-dimethyl-5-[(2-oxo-2, 3-dihydro-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid

Smiles: CC1=C(C=C2C3=CC=CC=C3NC2=O)NC(C)=C1CCC(O)=O

InChiKey: NHFDRBXTEDBWCZ-ZROIWOOFSA-N

InChi: InChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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