Ro 28-1675


Catalog No. Size PriceQuantity
M10544-2 Solid 2 mg $175
M10544-10 Solid 10 mg $575

Description

Ro 28-1675 is a potent allosteric GK activator with a SC1.5 value of 0.24± 0.0019 uM. Ro 28-1675 reduced fasting and postprandial glucose levels following an OGTT, was well tolerated, and displayed no adverse effects related to drug administration other than hypoglycemia at the maximum dose (400 mg).

Product information

CAS Number: 300353-13-3

Molecular Weight: 378.51

Formula: C18H22N2O3S2

Chemical Name: (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-(1,3-thiazol-2-yl)propanamide

Smiles: CS(=O)(=O)C1=CC=C(C=C1)[C@@H](CC1CCCC1)C(=O)NC1=NC=CS1

InChiKey: NEQSWPCDHDQINX-MRXNPFEDSA-N

InChi: InChI=1S/C18H22N2O3S2/c1-25(22,23)15-8-6-14(7-9-15)16(12-13-4-2-3-5-13)17(21)20-18-19-10-11-24-18/h6-11,13,16H,2-5,12H2,1H3,(H,19,20,21)/t16-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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