Description
CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor. CSV0C018875 exhibits lesser cytotoxicity than BIX-01294.
Product information
CAS Number: 442150-41-6
Molecular Weight: 312.79
Formula: C18H17ClN2O
Chemical Name: 6-chloro-N-(4-ethoxyphenyl)-2-methylquinolin-4-amine
Smiles: CC1=CC(NC2C=CC(=CC=2)OCC)=C2C=C(Cl)C=CC2=N1
InChiKey: NQNAQPVPGUVZAF-UHFFFAOYSA-N
InChi: InChI=1S/C18H17ClN2O/c1-3-22-15-7-5-14(6-8-15)21-18-10-12(2)20-17-9-4-13(19)11-16(17)18/h4-11H,3H2,1-2H3,(H,20,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
CSV0C018875 (2.5-20 μM; 48 hours) inhibits the levels of H3K9me2 modifications in the histones.
Products are for research use only. Not for human use.
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