EZH2-IN-5 - CAS# 1403258-69-4


Catalog No. Size PriceQuantity
M17837-C Contact sales@xcessbio.com for quotation $100

Description

EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively.

Product information

CAS Number: 1403258-69-4

Molecular Weight: 517.50

Formula: C26H37BrN4O2

Chemical Name: 5-Bromo-N-[(1, 2-dihydro-4, 6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-[[trans-4-(dimethylamino)cyclohexyl]ethylamino]-2-methylbenzamide

Smiles: CN(C)[C@@H]1CC[C@H](CC1)N(CC)C1=CC(Br)=CC(C(=O)NCC2C(=O)NC(C)=CC=2C)=C1C

InChiKey: FKKHGOZTTQASQA-MEMLXQNLSA-N

InChi: InChI=1S/C26H37BrN4O2/c1-7-31(21-10-8-20(9-11-21)30(5)6)24-14-19(27)13-22(18(24)4)25(32)28-15-23-16(2)12-17(3)29-26(23)33/h12-14,20-21H,7-11,15H2,1-6H3,(H,28,32)(H,29,33)/t20-,21-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC50 of 187.28 nM.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed