Rosuvastatin D3 - CAS# 1133429-16-9


Catalog No. Size PriceQuantity
M16382-C Contact sales@xcessbio.com for quotation $100

Description

Rosuvastatin D3 (ZD 4522 D3) is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals.

Product information

CAS Number: 1133429-16-9

Molecular Weight: 484.56

Formula: C22H28FN3O6S

Chemical Name: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(²H₃)methylmethanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid

Smiles: [2H]C([2H])([2H])N(C1N=C(C(/C=C/[C@@H](O)C[C@@H](O)CC(O)=O)=C(N=1)C(C)C)C1C=CC(F)=CC=1)S(C)(=O)=O

InChiKey: BPRHUIZQVSMCRT-UJWYGDJLSA-N

InChi: InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1/i3D3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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