Description
PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM.
Product information
CAS Number: 1407966-77-1
Molecular Weight: 523.63
Formula: C30H33N7O2
Chemical Name: (R)-3-(1-(1-acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3, 4-d]pyrimidin-3-yl)-N-(4-isopropyl-3-methylphenyl)benzamide
Smiles: CC1=CC(=CC=C1C(C)C)NC(=O)C1C=C(C=CC=1)C1=NN([C@H]2CN(CCC2)C(=O)C=C)C2=NC=NC(N)=C12
InChiKey: CGJVMKJGKFEHTL-HSZRJFAPSA-N
InChi: InChI=1S/C30H33N7O2/c1-5-25(38)36-13-7-10-23(16-36)37-29-26(28(31)32-17-33-29)27(35-37)20-8-6-9-21(15-20)30(39)34-22-11-12-24(18(2)3)19(4)14-22/h5-6,8-9,11-12,14-15,17-18,23H,1,7,10,13,16H2,2-4H3,(H,34,39)(H2,31,32,33)/t23-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 11 mg/mL (21.01 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.