PROTAC BRD4-DCAF1 degrader-1


Catalog No. Size PriceQuantity
M34144-C Contact sales@xcessbio.com for quotation $100

Description

PROTAC BRD4-DCAF1 degrader-1 (I-907) is a BRD4-DCAF1 PROTAC degrader, DC50 is 10~100 nM. (Pink: BRD4-DCAF1 ligand (HY-169152); Black: linker (HY-126976); Blue: E3 ligase ligand (HY-15846)).

Product information

CAS Number: 3036944-87-0

Molecular Weight: 1182.17

Formula: C60H64Cl2F2N8O9S

Smiles: CC1=NN=C2[C@H](CC(=O)NCCOCCOCCOCCOCCOCCCC3C=CC(=CC=3)C(=O)C3NC=C(C=3C3=C(F)C=CC(F)=C3C)C(=O)N[C@@H](CC(N)=O)C3=CC(Cl)=CC=C3)N=C(C3=C(SC(C)=C3C)N12)C1C=CC(Cl)=CC=1

InChiKey: QMEURCSLKDQIKL-GTMCEHENSA-N

InChi: InChI=1S/C60H64Cl2F2N8O9S/c1-35-37(3)82-60-53(35)55(40-14-16-43(61)17-15-40)68-49(58-71-70-38(4)72(58)60)33-51(74)66-20-22-78-24-26-80-28-30-81-29-27-79-25-23-77-21-6-7-39-10-12-41(13-11-39)57(75)56-54(52-36(2)46(63)18-19-47(52)64)45(34-67-56)59(76)69-48(32-50(65)73)42-8-5-9-44(62)31-42/h5,8-19,31,34,48-49,67H,6-7,20-30,32-33H2,1-4H3,(H2,65,73)(H,66,74)(H,69,76)/t48-,49-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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