Description
MPEP is a selective mGluR5 antagonist. MPEP reverses maze learning and PSD-95 deficits in Fmr1 knock-out mice. MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: significance for the use as anxiolytic/antidepressant drug.
Product information
CAS Number: 219911-35-0
Molecular Weight: 229.70
Formula: C14H12ClN
Chemical Name: 2-methyl-6-(2-phenylethynyl)pyridine hydrochloride
Smiles: Cl.CC1=CC=CC(C#CC2C=CC=CC=2)=N1
InChiKey: PKDHDJBNEKXCBI-UHFFFAOYSA-N
InChi: InChI=1S/C14H11N.ClH/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13;/h2-9H,1H3;1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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