Description
Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects.
Product information
CAS Number: 531-55-5
Molecular Weight: 305.83
Formula: C15H16ClN3S
Chemical Name: 3-(dimethylamino)-7-(methylamino)-5λ⁴-phenothiazin-5-ylium chloride
Smiles: [Cl-].CNC1=CC2=[S+]C3C=C(C=CC=3N=C2C=C1)N(C)C
InChiKey: KFZNPGQYVZZSNV-UHFFFAOYSA-M
InChi: InChI=1S/C15H16N3S.ClH/c1-16-10-4-6-12-14(8-10)19-15-9-11(18(2)3)5-7-13(15)17-12;/h4-9,16H,1-3H3;1H/q+1;/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Azure B (4-30 mg/kg; i.p.; once) decreases immobility in the forced swim test (FST).
Products are for research use only. Not for human use.
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