nAChR antagonist 1


Catalog No. Size PriceQuantity
M34052-C Contact sales@xcessbio.com for quotation $100

Description

nAChR antagonist 1 (compound B15) is an excellent α7 nAChR antagonist with an IC50 value of 3.3 μM. nAChR antagonist 1 can be used for researching schizophrenia, Alzheimer’s disease and inflammatory disorders[1].

Product information

Molecular Weight: 338.40

Formula: C19H22N4O2

Chemical Name: 3-[4-(2-methoxypyridin-4-yl)phenyl]-8-methyl-1-oxa-2, 4, 8-triazaspiro[4.5]dec-2-ene

Smiles: COC1=CC(=CC=N1)C1C=CC(=CC=1)C1NC2(CCN(C)CC2)ON=1

InChiKey: QDLDRBASXSECJO-UHFFFAOYSA-N

InChi: InChI=1S/C19H22N4O2/c1-23-11-8-19(9-12-23)21-18(22-25-19)15-5-3-14(4-6-15)16-7-10-20-17(13-16)24-2/h3-7,10,13H,8-9,11-12H2,1-2H3,(H,21,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Zhang H, et al. Design, synthesis and biological activities of piperidine-spirooxadiazole derivatives as α7 nicotinic receptor antagonists. Eur J Med Chem. 2020;207:112774

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed