Aspartyl-alanyl-diketopiperazine


Catalog No. Size PriceQuantity
M13936-2 2 mg solid $205
M13936-10 10 mg solid $510
M13936-100 100 mg solid $4,450
M13936-C Contact sales@xcessbio.com for quotation $100

Description

Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy.

Product information

CAS Number: 110954-19-3

Molecular Weight: 186.17

Formula: C7H10N2O4

Synonym:

DA-DKP

Chemical Name: 2-[(2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl]acetic acid

Smiles: C[C@@H]1NC(=O)[C@H](CC(O)=O)NC1=O

InChiKey: RVLCUCVJZVRNDC-IMJSIDKUSA-N

InChi: InChI=1S/C7H10N2O4/c1-3-6(12)9-4(2-5(10)11)7(13)8-3/h3-4H,2H2,1H3,(H,8,13)(H,9,12)(H,10,11)/t3-,4-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 125 mg/mL (671.43 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7.
  2. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41.

Products are for research use only. Not for human use.

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