Trifluoperazine N-Glucuronide - CAS# 165602-90-4


Catalog No. Size PriceQuantity
M17300-C Contact sales@xcessbio.com for quotation $100

Description

Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation.

Product information

CAS Number: 165602-90-4

Molecular Weight: 583.62

Formula: C27H32F3N3O6S

Chemical Name: 1-[(2R,3R,4S,5S,6S)-6-carboxylato-3,4,5-trihydroxyoxan-2-yl]-1-methyl-4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-ium

Smiles: C[N+]1(CCN(CCCN2C3=CC=CC=C3SC3=CC=C(C=C23)C(F)(F)F)CC1)[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C([O-])=O

InChiKey: AFYPHWNGUDUHIW-ARXROMJUSA-N

InChi: InChI=1S/C27H32F3N3O6S/c1-33(25-23(36)21(34)22(35)24(39-25)26(37)38)13-11-31(12-14-33)9-4-10-32-17-5-2-3-6-19(17)40-20-8-7-16(15-18(20)32)27(28,29)30/h2-3,5-8,15,21-25,34-36H,4,9-14H2,1H3/t21-,22-,23+,24-,25+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Trifluoperazine N-Glucuronide (1~10 μg; HEK293 cells) expression levels is 0.14 unit/mg protein. Trifluoperazine N-Glucuronide coexpression affects the activity of human UGT1A9. The imipramine N-glucuronide formation by the single expression system of trifluoperazine N-Glucuronide follows the Michaelis-Menten equation. Trifluoperazine N-Glucuronide interacts with the human UGT1A1 and UGT1A6, affecting the enzymatic activities.

Products are for research use only. Not for human use.

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