NOC-5 - CAS# 146724-82-5


Catalog No. Size PriceQuantity
M17356-C Contact sales@xcessbio.com for quotation $100

Description

NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors.

Product information

CAS Number: 146724-82-5

Molecular Weight: 176.22

Formula: C6H16N4O2

Chemical Name: (Z)-2-(3-aminopropyl)-1-(hydroxyimino)-2-(propan-2-yl)hydrazin-1-ium-1-olate

Smiles: CC(C)N(CCCN)/[N+](/[O-])=N/O

InChiKey: MTIRIKBRVALRPJ-NTMALXAHSA-N

InChi: InChI=1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,11H,3-5,7H2,1-2H3/b10-8-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

NOC-5 (5-20 μM) in PBS led to a rapid increase in NO release on day one. NOC-5 (100 μM, 24 h) activates only caspase-3; an increase in caspase-3 activity occurred after NO donor treatment: 1.62 (1.57-1.66) (P < 0.05). NOC-5 has pro-apoptotic action in Jurkat cells, but at the same time increased the level of anti-apoptotic proteins.

Products are for research use only. Not for human use.

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