Description
NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors.
Product information
CAS Number: 146724-82-5
Molecular Weight: 176.22
Formula: C6H16N4O2
Chemical Name: (Z)-2-(3-aminopropyl)-1-(hydroxyimino)-2-(propan-2-yl)hydrazin-1-ium-1-olate
Smiles: CC(C)N(CCCN)/[N+](/[O-])=N/O
InChiKey: MTIRIKBRVALRPJ-NTMALXAHSA-N
InChi: InChI=1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,11H,3-5,7H2,1-2H3/b10-8-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
NOC-5 (5-20 μM) in PBS led to a rapid increase in NO release on day one. NOC-5 (100 μM, 24 h) activates only caspase-3; an increase in caspase-3 activity occurred after NO donor treatment: 1.62 (1.57-1.66) (P < 0.05). NOC-5 has pro-apoptotic action in Jurkat cells, but at the same time increased the level of anti-apoptotic proteins.
Products are for research use only. Not for human use.
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