Description
APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases.
Product information
CAS Number: 2421110-28-1
Molecular Weight: 554.52
Formula: C24H29F3N6O6
Chemical Name: (2S)-1-[(2S)-5-carbamimidamido-2-[(1-hydroxynaphthalen-2-yl)formamido]pentanoyl]pyrrolidine-2-carboxamide; trifluoroacetic acid
Smiles: NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1=CC=C2C=CC=CC2=C1O.OC(=O)C(F)(F)F
InChiKey: FFLIQFBAKJNSSS-QJHJCNPRSA-N
InChi: InChI=1S/C22H28N6O4.C2HF3O2/c23-19(30)17-8-4-12-28(17)21(32)16(7-3-11-26-22(24)25)27-20(31)15-10-9-13-5-1-2-6-14(13)18(15)29;3-2(4,5)1(6)7/h1-2,5-6,9-10,16-17,29H,3-4,7-8,11-12H2,(H2,23,30)(H,27,31)(H4,24,25,26);(H,6,7)/t16-,17-;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide.
Products are for research use only. Not for human use.
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