Insulin (human)

Insulin (human) is a polypeptide hormone that regulates the level of glucose.

Product information

CAS Number: 11061-68-0

Molecular Weight: 5807.57

Formula: C257H383N65O77S6

Chemical Name: 4-({1-[(42-{[({1-[(1-{[({1-[(1-{[1-({1-[2-({5-amino-1-[(1-carboxy-2-hydroxypropyl)carbamoyl]pentyl}carbamoyl)pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-phenylethyl)carbamoyl]-2-phenylethyl}carbamoyl)methyl]carbamoyl}-4-carbamimidamidobutyl)carbamoyl]-3-carboxypropyl}carbamoyl)methyl]carbamoyl}-6-{2-[2-(2-{2-[2-(2-amino-3-phenylpropanamido)-3-methylbutanamido]-3-carbamoylpropanamido}-4-carbamoylbutanamido)-3-(1H-imidazol-4-yl)propanamido]-4-methylpentanamido}-77-(butan-2-yl)-47-[(2-carbamoyl-1-carboxyethyl)carbamoyl]-62-(2-carbamoylethyl)-53-(carbamoylmethyl)-24,56-bis(2-carboxyethyl)-83-(1-hydroxyethyl)-12,71,80-tris(hydroxymethyl)-33,50,65-tris[(4-hydroxyphenyl)methyl]-15-[(1H-imidazol-4-yl)methyl]-27-methyl-18,30,36,59,68-pentakis(2-methylpropyl)-7,10,13,16,19,22,25,28,31,34,37,40,49,52,55,58,61,64,67,70,73,76,79,82,85,87-hexacosaoxo-21,39-bis(propan-2-yl)-3,4,44,45,90,91-hexathia-8,11,14,17,20,23,26,29,32,35,38,41,48,51,54,57,60,63,66,69,72,75,78,81,84,86-hexacosaazabicyclo[72.11.7]dononacontan-88-yl)carbamoyl]-3-carbamoylpropyl}carbamoyl)-4-{2-[2-(2-aminoacetamido)-3-methylpentanamido]-3-methylbutanamido}butanoic acid

Smiles: CC1NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CO)NC(=O)CNC(=O)C(CSSCC2NC(=O)C(CSSCC(NC(=O)C(NC(=O)C(CO)NC(=O)C(NC2=O)C(C)O)C(C)CC)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC1=O)C(C)C)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC1C=CC=CC=1)C(=O)NC(CC1C=CC=CC=1)C(=O)NC(CC1C=CC(O)=CC=1)C(=O)NC(C(C)O)C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)NC(C(C)O)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(NC(=O)CN)C(C)CC)C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC1=CNC=N1)NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC1C=CC=CC=1)C(C)C)C(C)C

InChiKey: PBGKTOXHQIOBKM-UHFFFAOYSA-N

InChi: InChI=1S/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 16.67 mg/mL (2.87 mM; ultrasonic and adjust pH to 5 with HCl).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The human insulin gene contains two intervening sequences, one is within the region transcribed into the 5'-untranslated segment of the mRNA and the other interrupts the C-peptide encoding region. Human insulin is commonly used to treat type 2 diabetes.

Products are for research use only. Not for human use.