Description
Levosimendan is a calcium sensitizer that can cause increased cardiac contractility by binding troponin C, promotes vasodilation by activating ATP-sensitive potassium channels on vascular smooth muscle cells, and performs a cardioprotective function by prompting the opening of mitochondrial potassium channels in cardiomyocytes. It also has been reported to inhibit phosphodiesterases 3 and 4 in left ventricular cardiac tissue.
Product information
CAS Number: 141505-33-1
Molecular Weight: 280.28
Formula: C14H12N6O
Chemical Name: 1-cyano-N-{4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}methanecarbohydrazonoyl cyanide
Smiles: C[C@@H]1CC(=O)NN=C1C1C=CC(=CC=1)NN=C(C#N)C#N
InChiKey: WHXMKTBCFHIYNQ-SECBINFHSA-N
InChi: InChI=1S/C14H12N6O/c1-9-6-13(21)19-20-14(9)10-2-4-11(5-3-10)17-18-12(7-15)8-16/h2-5,9,17H,6H2,1H3,(H,19,21)/t9-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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